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Does Collagen Powder Make You Tired? Understanding the Connection Between Collagen and Fatigue
All About Collagen > Does Collagen Powder Make You Tired? Understanding the Connection Between Collagen and Fatigue

Does Collagen Powder Make You Tired? Understanding the Connection Between Collagen and Fatigue

07/08/2025 By Bubs Naturals

Table of Contents

  1. Introduction
  2. The Basics of Collagen
  3. The Connection Between Collagen and Fatigue
  4. Tips to Minimize Drowsiness from Collagen
  5. Conclusion
  6. FAQ

Have you ever found yourself wondering why you feel a bit more fatigued after incorporating collagen powder into your daily routine? You’re not alone. Many individuals, eager to reap the benefits of this popular supplement, have reported unexpected feelings of drowsiness or fatigue. So, does collagen powder really make you tired? Let's dive into the science and the nuances surrounding collagen supplementation, its effects on our bodies, and what you can do to mitigate any unwanted fatigue.

Introduction

Collagen is often hailed as a miracle supplement for skin health, joint support, and overall wellness. As the most abundant protein in our bodies, collagen makes up about 30% of our total protein content, providing structural integrity to our skin, bones, and connective tissues. As we age, the natural production of collagen declines, leading many of us to seek out collagen supplements to restore our youthful glow and vitality.

But amidst the buzz around collagen’s benefits, a curious phenomenon has emerged: some users report feeling unusually tired after taking collagen powder. This begs the question—could the very supplement that promises to enhance our wellness also be a culprit in causing fatigue?

In this blog post, we will explore the relationship between collagen powder and fatigue, examining the science behind how collagen affects our bodies, the potential mechanisms that could lead to drowsiness, and how to effectively incorporate collagen into your routine without the unwanted side effects. By the end, you’ll have a clearer understanding of whether collagen powder makes you tired and how to make the most of this wellness trend.

The Basics of Collagen

Before we delve into the potential fatigue associated with collagen powder, let’s first understand what collagen is and why it is essential for our health.

What is Collagen?

Collagen is a structural protein that plays a pivotal role in maintaining the strength and elasticity of connective tissues throughout the body. It is primarily composed of amino acids, particularly glycine, proline, and hydroxyproline. There are various types of collagen, with Type I being the most abundant in the human body, found mainly in skin, bones, tendons, and ligaments.

As we age, our bodies produce less collagen, which can lead to visible signs of aging such as wrinkles, sagging skin, and joint pain. This decline in collagen production has spurred the popularity of collagen supplements, which can come in various forms, including powders, capsules, and liquids.

Benefits of Collagen Supplements

Collagen supplements are often taken for a variety of reasons, including:

  • Improved skin health: Collagen is known to enhance skin elasticity and hydration, potentially reducing the appearance of fine lines and wrinkles.
  • Joint support: Many athletes and active individuals use collagen to support joint health and reduce discomfort associated with physical activity.
  • Gut health: Some research suggests that collagen may support gut health by strengthening the intestinal lining.

With these benefits in mind, it’s no wonder that collagen supplements have become a staple in many wellness routines. However, as we introduce collagen into our diets, it’s crucial to consider its effects beyond the surface.

The Connection Between Collagen and Fatigue

While many people report positive effects from collagen supplementation, some users experience unexpected fatigue. Let’s explore the potential reasons behind this phenomenon.

High Glycine Content

One of the key amino acids in collagen is glycine, which makes up about one-third of collagen’s total amino acid content. Glycine is known for its calming properties and has been shown to act as an inhibitory neurotransmitter in the brain. This can lead to a sense of relaxation, which may contribute to feelings of drowsiness in some individuals.

By boosting glycine levels, collagen supplementation may inadvertently encourage relaxation and sleepiness, particularly if taken during the day. If you find that collagen makes you feel tired, consider shifting your intake to the evening to align with your body's natural rhythms.

Increase in Tryptophan

Additionally, glycine can increase the levels of tryptophan in the brain. Tryptophan is a precursor to serotonin, which is then converted into melatonin, the hormone responsible for regulating sleep cycles. A rise in serotonin and melatonin levels could potentially lead to increased feelings of tiredness, especially if collagen is consumed at times when the body is not prepared for sleep.

Effects on Melatonin Secretion

As mentioned, collagen supplementation may influence melatonin production. Studies suggest that specific amino acids, including glycine, can stimulate the release of melatonin, further reinforcing the possibility of drowsiness following collagen intake. This interplay between collagen, glycine, tryptophan, and melatonin might explain why some individuals feel sleepy after taking collagen supplements.

Blood Sugar Changes

Another factor to consider is how collagen supplementation interacts with blood sugar levels. Collagen is a protein, and when it is taken on an empty stomach or combined with certain other nutrients, it may cause temporary fluctuations in blood sugar levels. For individuals who are sensitive to blood sugar changes, this could lead to feelings of fatigue or lethargy.

Tips to Minimize Drowsiness from Collagen

If you enjoy the benefits of collagen but find it makes you feel tired, don’t worry! There are several strategies you can implement to minimize any unwanted drowsiness:

1. Timing Matters

  • Try taking collagen in the evening. This allows its calming effects to work in your favor, promoting restful sleep rather than daytime fatigue.

2. Adjust Your Dosage

  • Start with a lower dosage of collagen and gradually increase as needed. This approach allows your body to adjust to the supplement without overwhelming your system.

3. Stay Hydrated

  • Ensure you’re drinking enough water throughout the day. Proper hydration can help mitigate blood sugar fluctuations, reducing feelings of fatigue.

4. Monitor Your Diet

  • Pay attention to what you consume alongside collagen. Avoid taking it on an empty stomach, and consider combining it with vitamin C-rich foods to enhance absorption without causing blood sugar dips.

5. Consult with a Professional

  • If fatigue persists, consult with a healthcare provider. They can help determine if your drowsiness is related to collagen or if other underlying factors may be at play.

Conclusion

In summary, while collagen powder can indeed contribute to feelings of drowsiness in some individuals, understanding its effects on neurotransmitters and melatonin production can help you navigate its impact on your energy levels. By adjusting the timing of your collagen intake, monitoring your dosage, and staying hydrated, you can enjoy the myriad benefits of collagen while minimizing any unwanted fatigue.

At BUBS Naturals, we are committed to providing high-quality, science-backed collagen supplements that support your wellness journey. Our Collagen Peptides are designed to blend seamlessly into your routine, offering a simple and effective way to enhance your health. Explore our full range of products, including our Hydrate Electrolytes and MCT Oil Powder, to support your active lifestyle with clean, functional ingredients.

FAQ

Q: Can collagen supplements make everyone tired?
A: Not everyone experiences drowsiness from collagen supplements. Individual responses vary based on sensitivity to amino acids like glycine and personal health factors.

Q: How should I take collagen to avoid fatigue?
A: Consider taking collagen in the evening to leverage its calming effects, and start with a lower dosage to see how your body reacts.

Q: Are there any side effects of collagen supplements?
A: Most people tolerate collagen well, but some may experience gastrointestinal discomfort or drowsiness. If side effects persist, consult a healthcare provider.

Q: Can I take collagen if I’m on medication?
A: Always consult with your healthcare provider before starting any new supplement, especially if you’re taking medications or have underlying health conditions.

By being mindful of how your body responds to collagen, you can harness its benefits for both skin health and overall wellness while managing your energy levels effectively.

*Disclaimer:

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Product results may vary from person to person.

Information provided on this site is solely for informational purposes only. It is not a substitute for professional medical advice. Do not use this information for diagnosing or treating a health problem or disease, or prescribing of any medications or supplements. Only your healthcare provider should diagnose your healthcare problems and prescribe treatment. None of our statements or information, including health claims, articles, advertising or product information have been evaluated or approved by the United States Food and Drug Administration (FDA). The products or ingredients referred to on this site are not intended to diagnose, treat, cure or prevent any disease. Please consult your healthcare provider before starting any supplement, diet or exercise program, before taking any medications or receiving treatment, particularly if you are currently under medical care. Make sure you carefully read all product labeling and packaging prior to use. If you have or suspect you may have a health problem, do not take any supplements without first consulting and obtaining the approval of your healthcare provider.

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